Doniphan is a town of roughly 1,800 people in one of the poorest counties in Missouri, where nearly 1 in 3 residents lives below the poverty line, the nearest hospital closed in 2018, and every elected official who represents them is a Republican who has voted for policies that make their lives harder. In 2026, that can change. This guide tells you exactly what is at stake, who is running, what the Republicans have done to this community, and why the Democrats challenging the